Publications

Minocycline restores olfactory bulb volume and olfactory behavior after traumatic brain injury in mice. Siopi E, Calabria S, Plotkine M, Marchand-Leroux C, Jafarian-Tehrani M. J Neurotrauma. 2011 Sep 12. [Epub ahead of print]

Simvastatin in traumatic brain injury: effect on brain edema mechanisms. Béziaud T, Ru Chen X, El Shafey N, Fréchou M, Teng F, Palmier B, Beray-Berthat V, Soustrat M, Margaill I, Plotkine M, Marchand-Leroux C, Besson VC. Crit Care Med. 2011 Oct;39(10):2300-7.

Minocycline Restores sAPPα Levels and Reduces the Late Histopathological Consequences of Traumatic Brain Injury in Mice. Siopi E, Cho AH, Homsi S, Croci N, Plotkine M, Marchand-Leroux C, Jafarian-Tehrani M. J Neurotrauma. 2011 Oct;28(10):2135-43.

Long-term histological and behavioural characterisation of a collagenase-induced model of intracerebral haemorrhage in rats. Beray-Berthat V, Delifer C, Besson VC, Girgis H, Coqueran B, Plotkine M, Marchand-Leroux C, Margaill I. J Neurosci Methods. 2010 Aug 30;191(2):180-90.

Effect of acute poly(ADP-ribose) polymerase inhibition by 3-AB on blood-brain barrier permeability and edema formation after focal traumatic brain injury in rats. Lescot T, Fulla-Oller L, Palmier B, Po C, Beziaud T, Puybasset L, Plotkine M, Gillet B, Meric P, Marchand-Leroux C. J Neurotrauma. 2010 Jun;27(6):1069-79.

Blockade of acute microglial activation by minocycline promotes neuroprotection and reduces locomotor hyperactivity after closed head injury in mice: a twelve-week follow-up study. Homsi S, Piaggio T, Croci N, Noble F, Plotkine M, Marchand-Leroux C, Jafarian-Tehrani M. J Neurotrauma. 2010 May;27(5):911-21.

Temporal and regional changes after focal traumatic brain injury. Lescot T, Fulla-Oller L, Po C, Chen XR, Puybasset L, Gillet B, Plotkine M, Meric P, Marchand-Leroux C. J Neurotrauma. 2010 Jan;27(1):85-94.

Minocycline effects on cerebral edema: relations with inflammatory and oxidative stress markers following traumatic brain injury in mice. Homsi S, Federico F, Croci N, Palmier B, Plotkine M, Marchand-Leroux C, Jafarian-Tehrani M. Brain Res. 2009 Sep 29;1291:122-32.

Combination therapy with fenofibrate, a peroxisome proliferator-activated receptor alpha agonist, and simvastatin, a 3-hydroxy-3-methylglutaryl-coenzyme A reductase inhibitor, on experimental traumatic brain injury. Chen XR, Besson VC, Beziaud T, Plotkine M, Marchand-Leroux C. J Pharmacol Exp Ther. 2008 Sep;326(3):966-74.

Housekeeping while brain's storming Validation of normalizing factors for gene expression studies in a murine model of traumatic brain injury. Rhinn H, Marchand-Leroux C, Croci N, Plotkine M, Scherman D, Escriou V. BMC Mol Biol. 2008 Jul 8;9:62.

Reduction of hemorrhagic transformation by PJ34, a poly(ADP-ribose)polymerase inhibitor, after permanent focal cerebral ischemia in mice. Haddad M, Beray-Berthat V, Coqueran B, Palmier B, Szabo C, Plotkine M, Margaill I. Eur J Pharmacol. 2008 Jun 24;588(1):52-7.

Plasma concentrations of arginine and related amino acids following traumatic brain injury: Proline as a promising biomarker of brain damage severity. Louin G, Neveux N, Cynober L, Plotkine M, Marchand-Leroux C, Jafarian-Tehrani M. Nitric Oxide. 2007 Sep;17(2):91-7.

Neurological recovery-promoting, anti-inflammatory, and anti-oxidative effects afforded by fenofibrate, a PPAR alpha agonist, in traumatic brain injury. Chen XR, Besson VC, Palmier B, Garcia Y, Plotkine M, Marchand-Leroux C. J Neurotrauma. 2007 Jul;24(7):1119-31.

Anti-inflammatory effects of PJ34, a poly(ADP-ribose) polymerase inhibitor, in transient focal cerebral ischemia in mice. Haddad M, Rhinn H, Bloquel C, Coqueran B, Szabó C, Plotkine M, Scherman D, Margaill I. Br J Pharmacol. 2006 Sep;149(1):23-30. Epub 2006 Jul 24.

Lack of iNOS induction in a severe model of transient focal cerebral ischemia in rats. Lerouet D, Jafarian-Tehrani M, Louin G, Palmier B, Bonnefont-Rousselot D, Plotkine M, Margaill I. Exp Neurol. 2005 Sep;195(1):218-28.

Time course of oxidative stress, lesion and edema after intrastriatal injection of malonate in rat: effect of alpha-phenyl-N-tert-butylnitrone. Paucard A, Besson VC, Plotkine M, Margaill I. Fundam Clin Pharmacol. 2005 Feb;19(1):57-64.

Biphasic modulation by nitric oxide of caspase activation due to malonate injection in rat striatum. Paucard A, Palmier B, Croci N, Taillieu F, Plotkine M, Margaill I. Eur J Pharmacol. 2004 Jan 12;483(2-3):259-65.

3-Aminobenzamide reduces brain infarction and neutrophil infiltration after transient focal cerebral ischemia in mice. Couturier JY, Ding-Zhou L, Croci N, Plotkine M, Margaill I. Exp Neurol. 2003 Dec;184(2):973-80.

Deleterious activation of poly(ADP-ribose)polymerase-1 in brain after in vivo oxidative stress. Besson VC, Margaill I, Plotkine M, Marchand-Verrecchia C. Free Radic Res. 2003 Nov;37(11):1201-8.

Polymorphonuclear neutrophils contribute to infarction and oxidative stress in the cortex but not in the striatum after ischemia-reperfusion in rats. Beray-Berthat V, Croci N, Plotkine M, Margaill I. Brain Res. 2003 Oct 10;987(1):32-8.

LF 16-0687 Ms, a bradykinin B2 receptor antagonist, reduces ischemic brain injury in a murine model of transient focal cerebral ischemia. Ding-Zhou L, Margaill I, Palmier B, Pruneau D, Plotkine M, Marchand-Verrecchia C. Br J Pharmacol. 2003 Aug;139(8):1539-47.

Neutrophils do not contribute to infarction, oxidative stress, and NO synthase activity in severe brain ischemia. Beray-Berthat V, Palmier B, Plotkine M, Margaill I. Exp Neurol. 2003 Aug;182(2):446-54.

Neuroprotective effects of (S)-N-[4-[4-[(3,4-Dihydro-6-hydroxy-2,5,7,8-tetramethyl-2H-1-benzopyran-2-yl)carbonyl]-1-piperazinyl]phenyl]-2-thiophenecarboximid-amide (BN 80933), an inhibitor of neuronal nitric-oxide synthase and an antioxidant, in model of transient focal cerebral ischemia in mice. Ding-Zhou L, Marchand-Verrecchia C, Palmier B, Croci N, Chabrier PE, Plotkine M, Margaill I. J Pharmacol Exp Ther. 2003 Aug;306(2):588-94.

Changes in oxidative stress, iNOS activity and neutrophil infiltration in severe transient focal cerebral ischemia in rats. Lerouet D, Beray-Berthat V, Palmier B, Plotkine M, Margaill I. Brain Res. 2002 Dec 20;958(1):166-75.

L-NAME reduces infarction, neurological deficit and blood-brain barrier disruption following cerebral ischemia in mice. Ding-Zhou L, Marchand-Verrecchia C, Croci N, Plotkine M, Margaill I. Eur J Pharmacol. 2002 Dec 20;457(2-3):137-46.