Ouriel Caën
ouriel.caen<at>parisdescartes.fr
27 years old
French, Israeli
LinkedIn
Ouriel is a biophysicist who develops new microfluidic technologies to tackle questions related to the emergence of resistance to targeted cancer therapies at the single-cell level. His research involves academic international collaborations (Max Planck Institute, Göttingen, Germany; Bordeaux University, France; EPFL, Switzerland) as well as industrial collaborations (Fluigent, Paris). He is now looking for opportunities in technological transfer.
TTO eDIAG platform
Université Sorbonne Paris Cité / FDV International PhD program, Paris, France.
Valérie Taly’s group, PhD student
• Directed evolution to highlight new cancer biomarkers using digital microfluidics
Collaboration with the Group of Jean Christophe Baret, Max Planck Institute of Göttingen (Germany)/ Univ. of Bordeaux (France).
Paris Diderot University, Center for Research and Interdisciplinarity, Paris, France
Master of Science (MSc) in Biophysics
L'Oréal, L'Oréal Research & Innovation / Department of Advanced Research, Skin Biophysics group, Aulnay-sous-Bois, France
• Modification of Stratum Corneum thermotropic behaviour by cosmetic formulations
ENEMA Electronics & Mechanics, Jerusalem, Israel
• Maximum Power Point Tracking of photovoltaic systems using extremum-seeking
Control and Matlab-Simulink modeling
SNCF, French National Railway Corporation, Paris, France
• Commercial officer
ESPCI, Patrick Tabeling’s group, Paris, France
• Droplet-based microfluidics for single neuron analysis to study Parkinson's disease in Drosophila
Institut Curie, Jean François Joanny’s group, Paris, France
• Mechanical control of cell flow in multicellular spheroids
Center for Research and Interdisciplinarity, iGEM competition, Paris, France
• “TuBe or not TuBe?” 2011: characterization of a new cell-to-cell bacterial communication system (via nanotubes) using synthetic constructs
Hebrew University of Jerusalem, Hadassah Medical Center, Assaf Zemel’s group , Jerusalem, Israel
• Dynamics of cell spreading, as a function of the kinetics of the lamellipodium-substrate interaction and the matrix rigidity
Design and organization of a two day microfluidics laboratory course for B.Sc. students
Supervision of M.Sc. intern Giorgos Pavlou (Interdisciplinary Approaches to Life Science (AIV) Master Program (M2))
Supervision of M.Sc. intern M.S.S. Jammalamadaka. (Interdisciplinary Approaches to Life Science (AIV) Master Program Student (M1))
Co-Supervision of bachelor intern Siddhansh Agarwal. Mechanical Engineering at Birla Institute of Technology & Science (BITS),Pilani, India.
Today PhD student at University of Illinois Urbana-Champaign, USA.
Supervision of master intern Aishah Prastowo (Interdisciplinary Approaches to Life Science (AIV) Master 2013 Program Student (M2)).
Today PhD student at Department of Engineering Science, University of Oxford, Oxford, UK.
ARC foundation, France
• 1 years PhD fellowship
French National Cancer Institute, France
• 3 years full PhD fellowship
MIT's International Genetically Engineered Machines competition (iGEM), Boston, USA
• First runner-up of European Championship, Best Presentation Prize
Accurate high-throughput cell counting using droplet-based microfluidics. H. Lu#, O. Caen#, J. Vrignon, P. Nizard, J-C. Baret, V. Taly. Scientific reports. In press. #Co-first name.
Multiplex Detection of Rare Mutations by Picoliter Droplet Based Digital PCR: Sensitivity and Specificity Considerations. Zonta E, Garlan F, Pécuchet N, Perez-Toralla K, Caen O, Milbury C, Didelot A, Fabre E, Blons H, Laurent-Puig P, Taly V. PLoS One. 2016 Jul 14;11(7):e0159094.
Parallelized ultra-high throughput microfluidic emulsifier for multiplex kinetic assays. Lim J, Caen O, Vrignon J, Konrad M, Taly V, Baret JC. Biomicrofluidics. 9(3):034101.
Pipette-and-play: parallelized ultra-high throughput microfluidic emulsifier for quantitative biochemical assays. J. Lim, O. Caen, J. Vrignon, M. Konrad, V. Taly and J.C. Baret.
In: Proceedings of the 18th International Conference on Miniaturized Systems for Chemistry and Life Sciences (MicroTAS), p. 258-260. ISBN: 978-0-9798064-7-6.
[Digital PCR compartmentalization II. Contribution for the quantitative detection of circulating tumor DNA]. Caen, O., Nizard, P., Garrigou, S., Perez-Toralla, K., Zonta, E., Laurent-Puig, P. and Taly, V.* Medecine/Sciences. 31(2):180-6.
Mechanical Control of Cell flow in Multicellular Spheroids. Morgan Delarue, Fabien Montel, Ouriel Caen, Jens Elgeti, Jean-Michel Siaugue, Danijela Vignjevic, Jacques Prost, Jean-François Joanny, and Giovanni Cappello. Phys. Rev. Lett. 110, 138103
Assessing cancer drug resistance at the single-cell level. NanoBiotech Montreux, Montreux (2016).
Pipette & play microfluidics: towards simple parallelization. IFP Energies nouvelles, Paris (2015).
Pipette-and-play: parallelized ultra-high throughput microfluidic emulsifier for quantitative biochemical assays. Conference on Miniaturized Systems for Chemistry and Life Sciences (MicroTAS), San Antonio, Texas (2014).
Pipette-and-play: parallelized ultra-high throughput microfluidic emulsifier for quantitative biochemical assays. GDR Micro Nano Systems-Micro Nano Fluidic. Ecole Polytechnique, Palaiseau - France. (2014).
Pipette & play microfluidics: towards simple parallelization. IFP Energies nouvelles, Paris. November 5th 2015.
Pipette & Play microfluidics. Towards simple parallelization. Fluigent workshop on microfluidics, Fluigent Headquarters, Villejuif, France. July 9th 2014.
Microfluidics, Cancer and Directed Evolution. Seminar. Interdisciplinary Fridays, Center for Research and Interdisciplinarity, Paris. France. June 14h 2013.
French (Native), Hebrew (Native), English (Full professional proficiency), Arabic (Elementary proficiency)