Publications Isabelle de Waziers 2010-2019

Hepatic Intra-arterial Delivery of a "Trojan-horses" Gene Therapy: A Pilot Study on Rabbit VX2 Hepatic Tumor Model. Pellerin O, Amara I, Sapoval M, Méachi T, Déan C, Beaune P, de Waziers I. Cardiovasc Intervent Radiol. 2018 Jan;41(1):153-162. doi: 10.1007/s00270-017-1833-8. Epub 2017 Oct 31

Engineered mesenchymal stem cells as vectors in a suicide gene therapy against preclinical murine models for solid tumors. Amara I, Pramil E, Senamaud-Beaufort C, Devillers A, Macedo R, Lescaille G, Seguin J, Tartour E, Lemoine FM, Beaune P, de Waziers I. J Control Release. 2016 Oct 10;239:82-91. doi: 10.1016/j.jconrel.2016.08.019. Epub 2016 Aug 23.

Knocking Down TMPRSS2-ERG Fusion Oncogene by siRNA Could be an Alternative Treatment to Flutamide. Urbinati G, de Waziers I, Slamiç M, Foussignière T, Ali HM, Desmaële D, Couvreur P, Massaad-Massade L. Mol Ther Nucleic Acids. 2016 Mar 29;5:e301. doi: 10.1038/mtna.2016.16.

Gene expression profiling of cytochromes P450, ABC transporters and their principal transcription factors in the amygdala and prefrontal cortex of alcoholics, smokers and drug-free controls by qRT-PCR. Toselli F, de Waziers I, Dutheil M, Vincent M, Wilce PA, Dodd PR, Beaune P, Loriot MA, Gillam EM. Xenobiotica. 2015;45(12):1129-37. doi: 10.3109/00498254.2015.1040102. Epub 2015 Jun 22.

Mesenchymal stem cells as cellular vehicles for prodrug gene therapy against tumors. Amara I, Touati W, Beaune P, de Waziers I. Biochimie. 2014 Oct;105:4-11. doi: 10.1016/j.biochi.2014.06.016. Epub 2014 Jun 27. Review.

Optimization and validation of a label-free MRM method for the quantification of cytochrome P450 isoforms in biological samples. Al Ali A, Touboul D, Le Caër JP, Schmitz-Afonso I, Flinois JP, Marchetti C, De Waziers I, Brunelle A, Laprévote O, Beaune P. Anal Bioanal Chem. 2014 Aug;406(20):4861-74. doi: 10.1007/s00216-014-7928-z. Epub 2014 Jun 22.

Important role of CYP2J2 in protein kinase inhibitor degradation: a possible role in intratumor drug disposition and resistance. Narjoz C, Favre A, McMullen J, Kiehl P, Montemurro M, Figg WD, Beaune P, de Waziers I, Rochat B. PLoS One. 2014 May 12;9(5):e95532. doi: 10.1371/journal.pone.0095532. eCollection 2014.

A suicide gene therapy combining the improvement of cyclophosphamide tumor cytotoxicity and the development of an anti-tumor immune response. Touati W, Tran T, Seguin J, Diry M, Flinois JP, Baillou C, Lescaille G, Andre F, Tartour E, Lemoine FM, Beaune P, de Waziers I. Curr Gene Ther. 2014;14(3):236-46.

Combined transcriptomic-(1)H NMR metabonomic study reveals that monoethylhexyl phthalate stimulates adipogenesis and glyceroneogenesis in human adipocytes. Ellero-Simatos S, Claus SP, Benelli C, Forest C, Letourneur F, Cagnard N, Beaune PH, de Waziers I. J Proteome Res. 2011 Dec 2;10(12):5493-502. doi: 10.1021/pr200765v. Epub 2011 Nov 9.

Colonization-induced host-gut microbial metabolic interaction. Claus SP, Ellero SL, Berger B, Krause L, Bruttin A, Molina J, Paris A, Want EJ, de Waziers I, Cloarec O, Richards SE, Wang Y, Dumas ME, Ross A, Rezzi S, Kochhar S, Van Bladeren P, Lindon JC, Holmes E, Nicholson JK. MBio. 2011 Mar 1;2(2):e00271-10. doi: 10.1128/mBio.00271-10. Print 2011.

[Could idiosyncratic thinking fit with << omics >>?]. Narjoz C, Beaune P, de Waziers I. Med Sci (Paris). 2010 Jun-Jul;26(6-7):641-6. doi: 10.1051/medsci/2010266-7641. Review. French.

Xenobiotic-metabolizing cytochromes p450 in human white adipose tissue: expression and induction. Ellero S, Chakhtoura G, Barreau C, Langouët S, Benelli C, Penicaud L, Beaune P, de Waziers I. Drug Metab Dispos. 2010 Apr;38(4):679-86. doi: 10.1124/dmd.109.029249.