GARLAN Fanny

French nationality
Born 19th March, 1988 in Ankara (Turkey)
E-mail: fanny.garlan<at>gmail.com
Linkedin

PhD student at Paris Descartes, Translational Research and Microfluidics team - ESPCI ParisTech Engineer

EXPERIENCE

Since Sept 2013 

PhD student at Paris Descartes, Lab.: Molecular Bases of Response to Xenobiotics, Pr Pierre Laurent-Puig; Team: Translational Research and Microfluidics, Dr Valérie Taly (supervisor). Doctoral school Frontières du Vivant ED 474.
Digital PCR in microdroplets to analyze circulating tumor DNA as part of personalized follow-up of patients suffering from colorectal cancer. 

Feb-Jul 2013 

MSc 6 months internship, French Alternative Energies and Atomic Energy Commission (CEA), Institute of Biomedical Imaging (I²BM), Molecular Imaging Research Center (MIRCen), Fontenay aux Roses, 92, France, http://www-dsv.cea.fr/MIRCen
Modelization of Alzheimer Disease in rodent: new approach using induction of Tau expression in the retina by intraocular injection of an AAV vector, follow-up of tau aggregation and consequences on axonal transport. Small animal surgery, immunohistochemistry, MRI.

May-July 2012 

Research Project at the University of Oxford, Department of Pharmacology. Development of clinically safe small molecules for treatment of bipolar disorder as an alternative to lithium. Technique: RT-PCR, enzymatic assay, ELISA.

July-December 2011 

Internship at NONY, Industrial Property Attorney (Paris), Patents engineering. Patents’ Writing, study of reports researches and answers to national offices, exploitation’s freedom bases.

July 2009 

Internship at TUNZINI (French Company of Heat Ventilation Air Conditioning engineering). Assessing ventilation systems figures.

July 2008 

Practical nurse at André Mignot hospital (Le Chesnay, France, 78). Help to patients (washing, eating), human relations, medicines distribution.

July-August 2006/7 

Hospital worker at André Mignot hospital (Le Chesnay, France, 78). Patients’ assistance, hygiene maintenance.

EDUCATION

2012-2013 

MSc student at Université Paris Descartes, BME Master MCB track. Immunology and genetic associated to current research on molecular therapy: viral vectors using AV, AAV, Lenti/Retroviruses; Cellular therapy: regenerative medicine and cell engineering, induced Pluripotent Stem cells.

2009-2012 

Student at ESPCI ParisTech, a graduate engineering school of physics, chemistry and biology, belonging to the top tier French graduate engineering schools, the ParisTech Group. 10 rue Vauquelin 75005 Paris (www.espci.fr)

2007-2009 

University-level preparation in physics and chemistry at Polytech’Paris-Sud, a French engineering school belonging to University of Orsay.

2006-2007 

PCEM 1: Ist year of medicine school, University of Versailles (France, 78). Alternative Ist year of university level.

2005-2006 

French scientific baccalauréat, secondary school leaving certificate, option Physics and Chemistry, awarded with honours.

LANGUAGES

French: Mother tongue
English: Upper intermediate skills
German: Intermediate skills

EXTRACURRICULAR ACTIVITIES

First Aid Diploma (April 2004)
Sports: swimming (3 years), hip-hop dance (7 years), cardio-training (4 years), skiing (16 years).
Interests: reading (Tsiolkas, Houellebecq, Reza, Gavalda, Pamuk).
Teaching: gave private tuition (mathematics, physics secondary school level, 2 hours/week, 1 year).

PUBLICATIONS AND COMMUNICATIONS

Papers in peer-reviewed journals (accepted or published)

Multiplex Detection of Rare Mutations by Picoliter Droplet Based Digital PCR: Sensitivity and Specificity Considerations. Zonta E, Garlan F, Pécuchet N, Perez-Toralla K, Caen O, Milbury C, Didelot A, Fabre E, Blons H, Laurent-Puig P, Taly V. PLoS One. 2016 Jul 14;11(7):e0159094. doi: 10.1371/journal.pone.0159094. eCollection 2016.

A Study of Hypermethylated Circulating Tumor DNA as a Universal Colorectal Cancer Biomarker. Garrigou S, Perkins G, Garlan F, Normand C, Didelot A, Le Corre D, Peyvandi S, Mulot C, Niarra R, Aucouturier P, Chatellier G, Nizard P, Perez-Toralla K, Zonta E, Charpy C, Pujals A, Barau C, Bouché O, Emile JF, Pezet D, Bibeau F, Hutchison JB, Link DR, Zaanan A, Laurent-Puig P, Sobhani I, Taly V. Clin Chem. 2016 Aug;62(8):1129-39. doi: 10.1373/clinchem.2015.253609.

[Digital PCR compartmentalization I. Single-molecule detection of rare mutations]. Perez-Toralla K, Pekin D, Bartolo JF, Garlan F, Nizard P, Laurent-Puig P, Baret JC, Taly V. Med Sci (Paris). 2015 Jan;31(1):84-92. doi: 10.1051/medsci/20153101017. Review. French.

Selected conferences

American Association for Cancer Research (AACR) 2016 meeting, April 2016, New Orleans, US. Prognostic value of circulating tumor DNA in advanced colorectal cancer patients: quantification of hypermethylated or mutant sequences using picoliter-droplet based digital PCR. Garlan F, Laurent-Puig P, Siauve N, Didelot A, Perkins G, Blons H, Taieb J, Taly V, Zaanan A. Poster.  

Nano Bio Tech Montreux-  November 17-19 2014 at Montreux- Switzerland. Picoliter droplet-based digital PCR to quantify circulating DNA in plasma of metastatic colorectal cancer patientsOral Presentation.